&lt;h2&gt;What is Avanafil (Spedra and Stendra)?&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Spedra (Avanafil) is a pharmaceutical remedy utilized to address erectile dysfunction (ED) or impotence in adult males. The group of drugs called phosphodiesterase type 5 (PDE5) inhibitors works by increasing blood flow to the penis, which helps men get an erection.&lt;/p&gt;
&lt;p&gt;The United States Food and Drug Administration (FDA) sanctioned Spedra in 2012, making it a relatively recent addition to the list of approved medications for erectile dysfunction. While it is marketed as Spedra Asia, it goes by the name Stendra in the United States.&lt;/p&gt;
&lt;h2&gt;&amp;nbsp;&lt;/h2&gt;
&lt;h2&gt;How effective is Avanafil?&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Researchers have found that avanafil is very good at raising the International Index of Erectile Function-Erectile Function (IIEF-EF) score, a test used to check for erectile dysfunction. Men who received this medication exhibited improvements across all dosage levels, ranging from 50mg to 200mg.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;How does Spedra (Avanafil) work?&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Spedra (Avanafil) fosters an increase in blood flow to the penis, which facilitates the initiation and sustenance of an erection during sexual activity. It is classified under the group of medications called phosphodiesterase type 5 (PDE5) inhibitors.&lt;/p&gt;
&lt;p&gt;When sexual stimulation occurs, nitric oxide is released within the penis, activating an enzyme called guanylate cyclase. It is this enzyme&#39;s job to make cyclic guanosine monophosphate (cGMP), which then makes the smooth muscles in the penis relax and open up. This relaxation of blood vessels allows for increased blood flow to the penis, resulting in an erection.&lt;/p&gt;
&lt;p&gt;Spedra does its job by stopping PDE5, an enzyme that breaks down cGMP, from doing its job. Spedra helps keep cGMP levels high in the penis by blocking PDE5. This keeps smooth muscle relaxation going and improves blood flow, which leads to an erection overall. It&#39;s essential to note that sexual stimulation remains a prerequisite for the effective action of Spedra.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;

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&lt;h2&gt;What are the causes of erectile dysfunction?&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Erectile dysfunction (ED) can stem from a variety of physical and psychological factors. Some of the most prevalent causes encompass:&lt;/p&gt;
&lt;ol&gt;
&lt;li&gt;&lt;strong&gt;Medical conditions: &lt;/strong&gt;diabetes, heart disease, high blood pressure, obesity, multiple sclerosis, Parkinson&#39;s disease, and &lt;a href=&quot;https://www.pulse-clinic.com/peyronies-disease&quot;&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;Peyronie&#39;s disease&lt;/strong&gt;&lt;/span&gt;&lt;/a&gt; are just a few of the illnesses that can cause ED.&lt;br /&gt;&lt;br /&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Lifestyle factors:&lt;/strong&gt; Unhealthy lifestyle practices such as smoking, excessive alcohol consumption, drug use, and a lack of exercise can heighten the risk of ED.&lt;br /&gt;&lt;br /&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Medications:&lt;/strong&gt; Certain medications, like antidepressants, antihistamines, and blood pressure drugs, can cause ED as a side effect.&lt;br /&gt;&lt;br /&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Psychological factors such as&lt;/strong&gt;&amp;nbsp;anxiety, stress, depression, and other mental health concerns can also contribute to ED.&lt;br /&gt;&lt;br /&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Hormonal imbalances:&lt;/strong&gt; Low levels of testosterone or other hormonal disparities can be a causal factor in ED.&lt;br /&gt;&lt;br /&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Aging:&lt;/strong&gt; The aging process can render men more susceptible to ED due to bodily changes over time.&lt;/li&gt;
&lt;/ol&gt;
&lt;p&gt;It&#39;s crucial to be aware that ED can be the result of a combination of several factors, and if you are experiencing ED, it&#39;s advisable to consult a healthcare professional to identify the underlying cause and devise an appropriate treatment plan.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;What are the treatments for erectile dysfunction?&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Individuals with &lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/erectile-dysfunction-treatment&quot;&gt;erectile dysfunction (ED) have a range of treatment&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt; options at their disposal. The choice of treatment depends on the underlying cause of ED, the severity of symptoms, and the overall health of the patient.&lt;/p&gt;
&lt;p&gt;Treatment for ED varies depending on the root cause, but common treatment modalities include:&lt;/p&gt;
&lt;ol&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Medicines:&lt;/strong&gt; Oral drugs like sildenafil (&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/buy-the-original-viagra-from-pulse-clinic-thailand-malaysia-singapore-hong-kong&quot;&gt;Viagra&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;), tadalafil (&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/buy-cialis&quot;&gt;Cialis&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;), avanafil (Spedra), and vardenafil (&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/buy-levitra-from-pulse-clinic-thailand-malaysia-singapore-hong-kong&quot;&gt;Levitra&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;) are often used to treat ED by increasing blood flow to the penis.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Lifestyle changes:&lt;/strong&gt; Making modifications to one&#39;s lifestyle, such as quitting smoking, reducing alcohol consumption, regular exercise, and maintaining a healthy weight, can be instrumental in improving ED.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Counseling:&lt;/strong&gt; Therapy or counseling can be invaluable in addressing the underlying psychological factors that may be contributing to ED.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Hormone therapy:&lt;/strong&gt; If ED is the result of low testosterone levels or other hormonal imbalances, hormone therapy may be prescribed.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Surgery:&lt;/strong&gt; In specific instances, surgery may be required to rectify underlying physical issues that give rise to ED.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;a href=&quot;https://www.pulse-clinic.com/shockwave-therapy-for-erectile-dysfunction-eswt&quot;&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;Shockwave therapy&lt;/strong&gt;&lt;/span&gt;&lt;/a&gt; is a non-invasive treatment for ED, it utilizes high-frequency acoustic waves to enhance blood flow and promote the development of new blood vessels in the penis.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;The Vacuum Therapy Device, &lt;/strong&gt;a&amp;nbsp;medical-grade penis pump, is &lt;a href=&quot;https://www.pulse-clinic.com.sg/vacuum-therapy-device-medical-penis-pump&quot;&gt;a vacuum device used for erectile dysfunction treatment that helps the penis get hard and maintain erection&lt;/a&gt;.&lt;/p&gt;
&lt;/li&gt;
&lt;/ol&gt;
&lt;p&gt;It&#39;s imperative to consult with a healthcare provider to ascertain the most suitable treatment approach for your specific needs.&lt;/p&gt;
&lt;/div&gt;
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