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&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;If you are looking for a genuine Spedra or Stendra or Generic Avanafil to be delivered to you discreetly, you can buy it from us online at PULSE Clinic. Please email us at&amp;nbsp;&lt;a href=&quot;mailto:info.silom@pulse-clinic.com&quot;&gt;info.bkk@pulse-clinic.com&lt;/a&gt;&amp;nbsp;or chat with us on your preferred platform.&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
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&lt;h2&gt;&amp;nbsp;&lt;/h2&gt;
&lt;h2&gt;What is Spedra (Avanafil)?&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Spedra (Avanafil) is a pharmaceutical treatment utilized for addressing erectile dysfunction (ED) or impotence in adult men. In the group of drugs called phosphodiesterase type 5 (PDE5) inhibitors, this one works by increasing blood flow to the penis, which helps men get an erection.&lt;/p&gt;
&lt;p&gt;Spedra is a relatively new addition to the list of second-generation oral medications for managing ED that the US Food and Drug Administration (FDA) has approved. While it is marketed as Spedra in Asia, in the United States, it is available under the name Stendra.&lt;/p&gt;
&lt;h2&gt;&amp;nbsp;&lt;/h2&gt;
&lt;h2&gt;How effective is Avanafil?&lt;/h2&gt;
&lt;hr /&gt;Avanafil has been shown to significantly improve the International Index of Erectile Function-Erectile Function (IIEF-EF) score, which is a tool used to evaluate erectile dysfunction. Individuals receiving this medication exhibited improvements across various doses, spanning from 50mg to 200mg.&lt;/div&gt;
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&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;How does Spedra (Avanafil) work?&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Spedra (Avanafil) facilitates increased blood circulation to the penis, which aids in the initiation and maintenance of an erection during sexual activity. It belongs to the class of medications called phosphodiesterase type 5 (PDE5) inhibitors.&lt;/p&gt;
&lt;p&gt;During sexual arousal, the release of nitric oxide in the penis activates an enzyme called guanylate cyclase. There is an enzyme called cGMP that helps make cyclic guanosine monophosphate. This enzyme then relaxes and opens up the smooth muscles in the penis. This relaxation of blood vessels allows for greater blood flow to the penis, ultimately leading to an erection.&lt;/p&gt;
&lt;p&gt;Spedra operates by inhibiting the action of PDE5, an enzyme responsible for breaking down cGMP. By blocking PDE5, Spedra helps maintain elevated levels of cGMP in the penis, leading to sustained relaxation of smooth muscles and improved blood flow, resulting in an erection. However, it&#39;s crucial to note that sexual stimulation remains a necessary component for the effective action of Spedra.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;If you are looking for a genuine Sperdra or Stendra or Generic Avanafil to be delivered to you discreetly, you can buy it from us online at PULSE Clinic. Please email us at&amp;nbsp;&lt;a href=&quot;mailto:info.silom@pulse-clinic.com&quot;&gt;info.bkk@pulse-clinic.com&lt;/a&gt;&amp;nbsp;or chat with us on your preferred platform.&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
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&lt;h2&gt;What are the causes of erectile dysfunction?&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Erectile dysfunction (ED) can stem from a variety of physical and psychological factors. Some of the most prevalent causes encompass:&lt;/p&gt;
&lt;ol&gt;
&lt;li&gt;&lt;strong&gt;Medical conditions: &lt;/strong&gt;diabetes, heart disease, high blood pressure, obesity, multiple sclerosis, Parkinson&#39;s disease, and &lt;a href=&quot;https://www.pulse-clinic.com/peyronies-disease&quot;&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;Peyronie&#39;s disease&lt;/strong&gt;&lt;/span&gt;&lt;/a&gt; are just a few of the illnesses that can cause ED.&lt;br /&gt;&lt;br /&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Lifestyle factors:&lt;/strong&gt; Unhealthy lifestyle practices such as smoking, excessive alcohol consumption, drug use, and a lack of exercise can heighten the risk of ED.&lt;br /&gt;&lt;br /&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Medications:&lt;/strong&gt; Certain medications like antidepressants, antihistamines, and blood pressure drugs can cause ED as a side effect.&lt;br /&gt;&lt;br /&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Psychological factors such as&lt;/strong&gt;&amp;nbsp;anxiety, stress, depression, and other mental health concerns can also contribute to ED.&lt;br /&gt;&lt;br /&gt;&lt;/li&gt;
&lt;li&gt;&lt;strong&gt;Hormonal imbalances:&lt;/strong&gt; Low levels of testosterone or other hormonal disparities can be a causal factor in ED.&lt;/li&gt;
&lt;li&gt;Aging: The aging process can render men more susceptible to ED due to bodily changes over time.&lt;/li&gt;
&lt;/ol&gt;
&lt;p&gt;It&#39;s crucial to be aware that ED can be the result of a combination of several factors, and if you are experiencing ED, it&#39;s advisable to consult a healthcare professional to identify the underlying cause and devise an appropriate treatment plan.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;h2&gt;What are the treatments for erectile dysfunction?&lt;/h2&gt;
&lt;hr /&gt;
&lt;p&gt;Individuals with &lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/erectile-dysfunction-treatment&quot;&gt;erectile dysfunction (ED) have a range of treatment&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt; options at their disposal. The choice of treatment depends on the underlying cause of ED, the severity of symptoms, and the overall health of the patient.&lt;/p&gt;
&lt;p&gt;Treatment for ED varies depending on the root cause, but common treatment modalities include:&lt;/p&gt;
&lt;ol&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Medicines:&lt;/strong&gt; Oral drugs like sildenafil (&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/buy-the-original-viagra-from-pulse-clinic-thailand-malaysia-singapore-hong-kong&quot;&gt;Viagra&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;), tadalafil (&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/buy-cialis&quot;&gt;Cialis&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;), avanafil (Spedra), and vardenafil (&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;&lt;a href=&quot;https://www.pulse-clinic.com/buy-levitra-from-pulse-clinic-thailand-malaysia-singapore-hong-kong&quot;&gt;Levitra&lt;/a&gt;&lt;/strong&gt;&lt;/span&gt;) are often used to treat ED by increasing blood flow to the penis.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Lifestyle changes:&lt;/strong&gt; Making modifications to one&#39;s lifestyle, such as quitting smoking, reducing alcohol consumption, regular exercise, and maintaining a healthy weight, can be instrumental in improving ED.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Counseling:&lt;/strong&gt; Therapy or counseling can be invaluable in addressing the underlying psychological factors that may be contributing to ED.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Hormone therapy:&lt;/strong&gt; If ED is the result of low testosterone levels or other hormonal imbalances, hormone therapy may be prescribed.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;strong&gt;Surgery:&lt;/strong&gt; In specific instances, surgery may be required to rectify underlying physical issues that give rise to ED.&lt;/p&gt;
&lt;/li&gt;
&lt;li&gt;
&lt;p&gt;&lt;a href=&quot;https://www.pulse-clinic.com/shockwave-therapy-for-erectile-dysfunction-eswt&quot;&gt;&lt;span style=&quot;text-decoration: underline;&quot;&gt;&lt;strong&gt;Shockwave therapy&lt;/strong&gt;&lt;/span&gt;&lt;/a&gt; is a non-invasive treatment for ED, it utilizes high-frequency acoustic waves to enhance blood flow and promote the development of new blood vessels in the penis.&lt;/p&gt;
&lt;/li&gt;
&lt;/ol&gt;
&lt;p&gt;It&#39;s imperative to consult with a healthcare provider to ascertain the most suitable treatment approach for your specific needs.&lt;/p&gt;
&lt;p&gt;&amp;nbsp;&lt;/p&gt;
&lt;hr /&gt;
&lt;p style=&quot;-qt-block-indent: 0; text-indent: 0px; margin: 0px;&quot;&gt;&lt;strong&gt;If you are looking for a genuine Sperdra or Stendra or Generic Avanafil to be delivered to you discreetly, you can buy it from us online with PULSE Clinic. Please email us at&amp;nbsp;&lt;a href=&quot;mailto:info.silom@pulse-clinic.com&quot;&gt;info.bkk@pulse-clinic.com&lt;/a&gt;&amp;nbsp;or chat with us on your preferred platform.&amp;nbsp;&lt;/strong&gt;&lt;/p&gt;
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